If you dreamed about a spider on your hand: You may find it difficult to cope with challenging conditions in your business life, you may have to deal with new issues related to money. To see a spider on your hand in your dream refers to collecting good deeds, wishing for the good, a lucky person and chasing after the good. To kill a spider on one's hand in a dream indicates sin and hard times, life being turned upside down and falling out of favor.